Comparing Fast Pressure Jump and Temperature Jump Protein Folding Experiments and Simulations
نویسندگان
چکیده
منابع مشابه
Comparing Fast Pressure Jump and Temperature Jump Protein Folding Experiments and Simulations.
The unimolecular folding reaction of small proteins is now amenable to a very direct mechanistic comparison between experiment and simulation. We present such a comparison of microsecond pressure and temperature jump refolding kinetics of the engineered WW domain FiP35, a model system for β-sheet folding. Both perturbations produce experimentally a faster and a slower kinetic phase, and the "sl...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2015
ISSN: 0002-7863,1520-5126
DOI: 10.1021/jacs.5b02474